Fidelity bank banner Atiku Obi Campaign banner Newsexpress banner Camano banner
Scientists take step toward creating artificial life

By News Express on 01/12/2017

Share on facebook Yahoo mail icon Gmail icon Share on Google+

Views: 846

•DNA
•DNA

In a major step toward creating artificial life, U.S. researchers have developed a living organism that incorporates both natural and artificial DNA and is capable of creating entirely new, synthetic proteins.

The work, published in the journal Nature, brings scientists closer to the development of designer proteins made to order in a laboratory.

Previous work by Floyd Romesberg, a chemical biologist at the Scripps Research Institute in La Jolla, California, showed that it was possible to expand the genetic alphabet of natural DNA beyond its current four letters: adenine (A), cytosine(C), guanine (G) and thymine(T).

In 2014, Romesberg and colleagues created a strain of E. coli bacteria that contained two unnatural letters, X and Y.

In the latest work, Romesberg’s team has shown that this partially synthetic form of E. coli can take instructions from this hybrid genetic alphabet to make new proteins.

“This is the first time ever a cell has translated a protein using something other than G, C, A or T,” Romesberg said.

Although the actual changes to the organism were small, the feat is significant, he said in a telephone interview. “It’s the first change to life ever made.”

Objective: Treatments for diseases

It’s a goal Romesberg has been working toward for 20 years. Creating new forms of life, however, is not the main point. Romesberg is interested in using this expanded genetic alphabet to create new types of proteins that can be used to treat disease.

In 2014, he formed a company called Synthorx Inc., which is working on developing new protein-based treatments.

“A lot of proteins that you want to use as drugs get cleared in the kidney very quickly,” Romesberg said. The new system would allow scientists to attach fat molecules to drugs to keep them in the body longer.

Romesberg is aware that the creation of semisynthetic organisms might raise concerns of hybrid life forms spreading beyond the lab, but the system they used makes such an escape unlikely.

For example, in natural DNA, base pairs are attracted to each other through the bonding of hydrogen atoms. Romesberg’s X and Y bases are attracted through an entirely different process, which prevents them from accidentally bonding with natural bases.

And because cells cannot make their own X and Y without the addition of certain chemicals, the semisynthetic organisms cannot live outside a laboratory.

“They can’t escape,” Romesberg said. “There’s no ‘Jurassic Park’ scenario.” (Reuters)


 

Source News Express

Posted 01/12/2017 9:16:46 PM

 

Share on facebook Yahoo mail icon Gmail icon Share on Google+


 

CLASSIFIED ADS

 

You may also like...
Customs seizes N50m Indian hemp in Kebbi

Super Eagles to battle Greece, USA ahead Brazil...

Nigeria needs restructuring, not elections, By Leke Agbarin-Agba...

Obasa emerges as new Chairman Conference of Speakers...

National Conference shifts to NICON Luxury Hotel as...

Nigeria not ungovernable despite challenges — Bishop Bagobiri...

First Bank launches WhatsApp banking

Union threatens to ground Caverton Helicopters over sack...

Bob Miga, musical genius behind One World, Black...

Gov Udom Emmanuel not interested in white elephant...

Research institutes’ workers begin warning strike

Shittu: FG to include artificial intelligence AI and...

 

Latest News Conduct Bureau adamant on CJN Onnoghen’s trial; serves criminal charges •Why trial may go ahead despite court order Minimum Wage: Labour promises ‘hell’ for dissenting governors Andy Uba moves to establish university in Anambra Nigerian Ambassador dies in Abidjan I feel very sad about CJN Onnoghen’s trial — Osinbajo 2,551 suspected thieves arrested in Kaduna Crocodile mauls woman to death Imo APC commences contempt proceedings against Oshiomhole PSC warns against illegal transfers of commissioners ahead of elections 2019: Saraki warns against do-or-die politics •Says Nigerians must be allowed to elect candidates of their choice National Assembly adjourns after resumption from Yuletide break Promotion withdrawal: Oyo workers begin warning strike

 

Most Read NUDE PHOTO OF OMOTOLA JALADE-EKEINDE surfaces online (439,801 views) Nigerian female sex addict opens up, says ‘I like it with both men and women’ (399,698 views) Shameless Genevieve Nnaji exposes breasts in public (333,161 views) Finally named: The full list of friends of Nigerian female sex addict who prowled Facebook (286,368 views) OLUMBA OLUMBA OBU (the one who called himself God) IS DEAD (251,872 views) Igbo scholar disgraces Femi Fani-Kayode •Demolishes claims on Igbo/Yoruba history with facts and figures (231,286 views) Breaking News: POPULAR REVEREND CONVERTS TO ISLAM in Kaduna (Nigeria) (215,282 views) OBJ’s son reported dead in Lagos plane crash •Names of more victims emerge (196,458 views) My wasted years in Olumba Olumba Obu’s Evil Brotherhood (183,670 views) THE FINAL DISGRACE: Igbo scholar unleashes more facts about Igbo/Yoruba history, finishes off Femi Fani-Kayode with second article (172,336 views) Lagos plane crash: Journalist releases victims’ names (169,722 views) Gunmen kill ASP, 2 other police officers in vain bid to kidnap Rivers PDP chieftain (155,720 views)

 

JAMB 2019 Reg

CBN banner

 

Categories Advertorials (3) African Press Organisation (81) Art & Literature (76) Business & Economy (3,955) Business Verdict (54) Columnists (982) Complaints & Requests (95) Enterprise & Opportunities (208) Entertainment (579) Features (703) Global Business Monitor (314) International (2,983) Interview (170) Live Commentary (28) Love Matters (151) Maggie's Blog (112) News (42,442) Opinion (1,179) Pidgin (16) Politics (8,723) Religion (941) Sports (1,862) Stock Watch (36) AMA & Al Jazeera Global Update

 

 

 

 

APO Group Partner

 

 

CLASSIFIED ADS

GOCOP Accredited Member

GOCOP Accredited member

 

 

Africa Media Agency and Al Jazeera