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Breakthrough in Ebola treatment

By Carol Pearson on 14/01/2019

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In northeastern Congo, more than 600 people have fallen ill with the Ebola virus, and at least 368 people have died from the disease. It’s been difficult to contain the virus because of conflict in the region, despite medical advances, including a vaccine.

The Democratic Republic of Congo is where Ebola was first discovered in 1976, when the country was called Zaire. The disease was named after the Ebola River where the virus was spreading. Between then and 2013, there was no treatment or a vaccine. The outbreak ran its course in quarantined communities.

Scientists started studying the virus, however, trying to come up with better ways to handle its various deadly strains. They succeeded in producing a vaccine to help end the Ebola epidemic that swept through three West African countries between 2013 and 2016. More than 11,000 people died in that outbreak.

Treatment found

At that time, treatment for the Zaire strain of Ebola was developed. It was costly to produce and didn’t work on two other lethal strains, the Sudan and Bundibugyo viruses.

But now scientists have found one. Their research produced a drug cocktail called MBP134 that helped monkeys infected with three deadly strains of Ebola recover from the disease.

What’s more, the treatment requires a single intravenous injection.

Thomas Geisbert, Ph.D., led the research at the University of Texas Medical Branch, part of a public-private partnership that also included Mapp Biopharmaceutical, the U.S. Army Research Institute of Infectious Diseases, and the Public Health Agency of Canada.

Must treat all strains

In an interview with VOA, Geisbert stressed the need for a treatment that would be effective against all strains of Ebola.

“When an outbreak occurs, we really don’t know which one of those three strains, species, we call them, is the cause of that particular episode,” Geisbert said.

He added that the treatments available have been effective only against the Zaire species, which leaves people infected with the other species unprotected.

“Our goal was to develop a treatment that would work regardless of the particular strain of Ebola that was causing it,” Geisbert said.

“If I have to make a drug that only works against Zaire, and another drug that only works against Sudan and another drug that only works against the Bundibugyo species, that is extremely expensive,” he added.

Geisbert said the treatment will save valuable time in determining which strain of Ebola is circulating in a particular outbreak. It will save lives because people can be treated immediately, and it will also save money. (VOA)

A Congolese health worker administers Ebola vaccine to a woman who had contact with an Ebola sufferer in the Democratic Republic of Congo, Aug. 18, 2018.

Source News Express

Posted 14/01/2019 10:48:23 AM

 

 

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