NewsExpress advert Yudala banner
Scientists take step toward creating artificial life

By News Express on 01/12/2017

Share on facebook Yahoo mail icon Gmail icon Share on Google+

Views: 485

•DNA
•DNA

In a major step toward creating artificial life, U.S. researchers have developed a living organism that incorporates both natural and artificial DNA and is capable of creating entirely new, synthetic proteins.

The work, published in the journal Nature, brings scientists closer to the development of designer proteins made to order in a laboratory.

Previous work by Floyd Romesberg, a chemical biologist at the Scripps Research Institute in La Jolla, California, showed that it was possible to expand the genetic alphabet of natural DNA beyond its current four letters: adenine (A), cytosine(C), guanine (G) and thymine(T).

In 2014, Romesberg and colleagues created a strain of E. coli bacteria that contained two unnatural letters, X and Y.

In the latest work, Romesberg’s team has shown that this partially synthetic form of E. coli can take instructions from this hybrid genetic alphabet to make new proteins.

“This is the first time ever a cell has translated a protein using something other than G, C, A or T,” Romesberg said.

Although the actual changes to the organism were small, the feat is significant, he said in a telephone interview. “It’s the first change to life ever made.”

Objective: Treatments for diseases

It’s a goal Romesberg has been working toward for 20 years. Creating new forms of life, however, is not the main point. Romesberg is interested in using this expanded genetic alphabet to create new types of proteins that can be used to treat disease.

In 2014, he formed a company called Synthorx Inc., which is working on developing new protein-based treatments.

“A lot of proteins that you want to use as drugs get cleared in the kidney very quickly,” Romesberg said. The new system would allow scientists to attach fat molecules to drugs to keep them in the body longer.

Romesberg is aware that the creation of semisynthetic organisms might raise concerns of hybrid life forms spreading beyond the lab, but the system they used makes such an escape unlikely.

For example, in natural DNA, base pairs are attracted to each other through the bonding of hydrogen atoms. Romesberg’s X and Y bases are attracted through an entirely different process, which prevents them from accidentally bonding with natural bases.

And because cells cannot make their own X and Y without the addition of certain chemicals, the semisynthetic organisms cannot live outside a laboratory.

“They can’t escape,” Romesberg said. “There’s no ‘Jurassic Park’ scenario.” (Reuters)


 

Source News Express

Posted 01/12/2017 9:16:46 PM

 

Share on facebook Yahoo mail icon Gmail icon Share on Google+


 

CLASSIFIED ADS

Loss Off Your Belly Fats, Upper Arm Fat and Body Fats In 2weeks Time.. Click HERE To Start Now!

Let us build the most comprehensive online database of worthy and credible Nigerians from all walks of life. It is worth doing!

 

You may also like...
I collapsed twice in DSS custody —Ekiti lawmaker...

Abuja snacks seller turns millionaire overnight

ICPC decries increasing cases of corruption in tertiary...

The most important skill for a successful entrepreneur...

Secondus unfolds agenda as PDP Chairman •His plan...

Ofuani unveils strategy for integrated development of Asaba...

Dambazau and Nigeria’s Internal Security, By Muhammad Ajah...

World Bank approves $575m scale up support for...

Colonel beats General to emerge Burkina Faso’s new...

Okowa hails Gbaramatu Monarch on Coronation Anniversary

THE ILLUSION OF BARRACKS OPTION, by Olusegun Adeniyi...

BREAKING NEWS: Kidnapped Lagos students rescued

 

Latest News Buhari’s son rumoured dead but Presidency says very much alive Yobe school attack: 2 girls reported dead, 13 still missing Stop extorting money from innocent Igbo traders, Okorocha tells Customs Teleology emerges 9mobile preferred bidder, given 21 days to deposit non-refundable $50m Court declares daytime curfew of Oro festival illegal in Ogun FG to invest in modular refineries PDP expresses shock over missing Dapchi school girls, tasks Police IG Budget Minister briefs National Assembly leadership on economic recovery focus labs Ekiti movement releases ‘Neighbor to Neighbor’ outreach timetable for Fayose’s preferred successor African migrants begin hunger strike over Israel policy Delta State Government seeks parents’ support for measles vaccination campaign NSCDC officials who shot Bayelsa youths acted in self-defence: State Commandant

 

Most Read Nigerian female sex addict opens up, says ‘I like it with both men and women’ (326,130 views) NUDE PHOTO OF OMOTOLA JALADE-EKEINDE surfaces online (317,831 views) Shameless Genevieve Nnaji exposes breasts in public (254,578 views) Finally named: The full list of friends of Nigerian female sex addict who prowled Facebook (208,817 views) Igbo scholar disgraces Femi Fani-Kayode •Demolishes claims on Igbo/Yoruba history with facts and figures (194,694 views) OLUMBA OLUMBA OBU (the one who called himself God) IS DEAD (187,621 views) Breaking News: POPULAR REVEREND CONVERTS TO ISLAM in Kaduna (Nigeria) (163,304 views) OBJ’s son reported dead in Lagos plane crash •Names of more victims emerge (146,629 views) THE FINAL DISGRACE: Igbo scholar unleashes more facts about Igbo/Yoruba history, finishes off Femi Fani-Kayode with second article (140,339 views) Lagos plane crash: Journalist releases victims’ names (129,495 views) My wasted years in Olumba Olumba Obu’s Evil Brotherhood (127,987 views) Gunmen kill ASP, 2 other police officers in vain bid to kidnap Rivers PDP chieftain (123,083 views)

 

Categories Advertorials (3) African Press Organisation (81) Art & Literature (34) Business (2,899) Business Verdict (34) Columnists (804) Complaints & Requests (94) Enterprise & Opportunities (203) Entertainment (446) Features (549) Global Business Monitor (226) International (1,799) Interviews (143) Live Commentary (28) Love Matters (105) News (33,033) Opinion (883) Pidgin (10) Politics (4,512) Religion (681) Sports (1,438) Stock Watch (28) AMA & Al Jazeera Global Update

 

 

Football president George Weah puts Liberian army to the test

 

APO Group Partner

 

CLASSIFIED ADS

Let us build the most comprehensive online database of worthy and credible Nigerians from all walks of life. It is worth doing!

Loss Off Your Belly Fats, Upper Arm Fat and Body Fats In 2weeks Time.. Click HERE To Start Now!

GOCOP Accredited Member

GOCOP Accredited member

 

 

Africa Media Agency and Al Jazeera

Advertisement