Shell Energy Entrepreneurs banner Yudala banner
New genetic discovery may eventually end premature birth

By Carol Pearson on 11/09/2017

Share on facebook Yahoo mail icon Gmail icon Share on Google+

Views: 534


 Researchers have found genetic mutations that affect whether a woman is likely to have her baby early or carry it to full term.

Even late preterm babies, those born between 34 and 36 weeks of gestation, are more likely to die or experience problems, even if they are the size and weight of some full-term infants born after 37 to 41 weeks in the womb.

Preterm birth is the leading cause of death among children younger than 5 worldwide. These babies have higher death rates even into adolescence and beyond.

Several studies show health problems related to preterm birth persist through adult life, problems such as chronic lung disease, developmental handicaps, vision and hearing losses. The World Health Organization reports that every year, an estimated 15 million babies are born early, and this number is rising. Until now, little was known about the causes, but these findings could help solve the mystery.

Beginning of a journey

Dr. Louis Muglia coordinated the study of the DNA of more than 50,000 pregnant women. The study identified six gene regions, which influence the length of pregnancy and the timing of birth. While the study doesn’t provide information about how to prevent prematurity, Muglia says it could eventually do that.

“It’s just the beginning of the journey, but at least we know now, what the foundation is,” he says.

Muglia is co-director of the Perinatal Institute, which focuses on preterm babies, at Cincinnati Children’s Hospital Medical Center. He’s also the principal investigator of one of the March of Dimes’ five prematurity research centers. The March of Dimes helped pay for the study along with the National Institutes of Health, the Bill and Melinda Gates Foundation and other medical research institutes.

Muglia said scientists have known for a long time that preterm birth is a combination of genetic and environmental factors. This study showed the genes involved were from the mother.

“For the first time, we have an idea of what tissue in the mom is the one that is likely driving the one for preterm birth,” Muglia says.

Selenium

One of the genes identified is involved in how the body uses selenium, a common mineral provided in food or supplements, but not currently included in vitamins women commonly take while pregnant. Selenium supplements are low-cost, and if the results are confirmed, this supplement could save millions of lives. Supplements including folic acid have been shown to greatly reduce birth defects, so much so that food in many countries is fortified with this particular B vitamin.

Another gene indicated that cells that line the uterus play a larger-than-expected role in the length of pregnancy.

The researchers were from the U.S. and from Norway, Denmark, Finland and Sweden. They only tested women of European descent, so more work needs to be done involving women of other races and ethnic origins.

But their study does open up areas for researching potential diagnostic tests, new medications, improved dietary supplements or other changes that could help more women have full-term pregnancies, all areas which will require several more years of study.

Courtesy of the New England Journal of Medicine.

Coordinated the study, Dr. Louis Muglia

Source News Express

Posted 11/09/2017 9:12:55 PM

 

Share on facebook Yahoo mail icon Gmail icon Share on Google+


 

CLASSIFIED ADS

Let us build the most comprehensive online database of worthy and credible Nigerians from all walks of life. It is worth doing!

Loss Off Your Belly Fats, Upper Arm Fat and Body Fats In 2weeks Time.. Click HERE To Start Now!

 

You may also like...
Ex-militants threaten to resume armed struggle, cripple oil...

China declares support for war against Boko Haram,...

5,000 vehicles powered on CNG in Nigeria –...

How the Premiership battles ended (Plus the table)...

Boko Haram sets up base in Bauchi forest...

2015: Politicians out to blackmail Governor Akpabio —Commissioner...

Investors upbeat as capitalisation gains N1.82tr in four...

Reps order CBN to suspend new capital base...

Ghost worker on trial over N11m fraud

Random musings on constitutional amendments

Olonishakin meets Buratai, expresses satisfaction with battle against...

Brazil 2014 World Cup: Keshi’s list raises eyebrows,...

 

Latest News Court orders release of 475 Boko Haram suspects for rehabilitation Confession of a rituals: I pay N10,000 for virgins' underwears FG deploys Agro Rangers to end herders-farmers’ clashes Lassa Fever: Delta places 24 under surveillance; confirms 3 deaths, 7 cases Get Shekau dead or alive, Buratai charges troops Dangote, others for Editors’ Plaza foundation-laying ceremony Air Peace passenger steals N1m on board flight, faces trial 2019: Niger APC endorses President Buhari, Governor Sani Bello •Receives 34,000 decampees IG deploys 3 additional Police Mobile Force units to Zamfara in bid to end killings Florida school shooting: Students to march on Washington Saraki invites child comedienne Emmanuella to the Senate NiMet predicts cloudy skies for Monday

 

Most Read Nigerian female sex addict opens up, says ‘I like it with both men and women’ (324,811 views) NUDE PHOTO OF OMOTOLA JALADE-EKEINDE surfaces online (316,351 views) Shameless Genevieve Nnaji exposes breasts in public (252,960 views) Finally named: The full list of friends of Nigerian female sex addict who prowled Facebook (207,641 views) Igbo scholar disgraces Femi Fani-Kayode •Demolishes claims on Igbo/Yoruba history with facts and figures (194,054 views) OLUMBA OLUMBA OBU (the one who called himself God) IS DEAD (186,642 views) Breaking News: POPULAR REVEREND CONVERTS TO ISLAM in Kaduna (Nigeria) (162,179 views) OBJ’s son reported dead in Lagos plane crash •Names of more victims emerge (145,540 views) THE FINAL DISGRACE: Igbo scholar unleashes more facts about Igbo/Yoruba history, finishes off Femi Fani-Kayode with second article (139,794 views) Lagos plane crash: Journalist releases victims’ names (128,684 views) My wasted years in Olumba Olumba Obu’s Evil Brotherhood (127,168 views) Gunmen kill ASP, 2 other police officers in vain bid to kidnap Rivers PDP chieftain (122,520 views)

 

Categories Advertorials (3) African Press Organisation (81) Art & Literature (34) Business (2,894) Business Verdict (33) Columnists (802) Complaints & Requests (94) Enterprise & Opportunities (203) Entertainment (445) Features (548) Global Business Monitor (225) International (1,796) Interviews (143) Live Commentary (28) Love Matters (104) News (32,923) Opinion (883) Pidgin (10) Politics (4,503) Religion (677) Sports (1,433) Stock Watch (27) AMA & Al Jazeera Global Update

 

CBN Banner advert

CBN Words on marble

 

 

Football president George Weah puts Liberian army to the test

 

APO Group Partner

 

CLASSIFIED ADS

Let us build the most comprehensive online database of worthy and credible Nigerians from all walks of life. It is worth doing!

Loss Off Your Belly Fats, Upper Arm Fat and Body Fats In 2weeks Time.. Click HERE To Start Now!

GOCOP Accredited Member

GOCOP Accredited member

 

 

Africa Media Agency and Al Jazeera

Advertisement